- Systemic disorders of hemostasis that can contribute to heavy menstrual bleeding (i.e. hemophilia, von Willebrand disease)
- Heavy menstrual bleeding since menarche History of hemorrhage (after delivery, during surgery or dental work), easy bruising, epistaxis, gum bleeding
- Family history of bleeding problems
- Structured medical history can identify coagulopathy in approximately 90% of cases
- Multidisciplinary approach recommended
- Treatment often involves tranexamic acid usually in combination with hormonal treatments. NSAIDs should not be prescribed
- Surgical treatment may be required in refractory cases
- Bacon JL, et al. Obstet Gynecol Clin North Am 2017;44:179–93.
- Singh S, et al. J Obstet Gynaecol Can 2013;35(5_eSuppl):S1–S28.
- Kouides PA, et al. Fertil Steril 2005;84:1345–51.
- Whitaker L and Critchley HOD. Best Pract Res Clin Obstet Gynecol 2016;34:54–65.